J-1500 Circular Dichroism Spectrometer
The new JASCO J-1500 is designed to meet the most demanding of CD applications. The performance level is unparalleled and the layout is suited for adaptation to a variety of different sampling methods. With CD, LD and Absorbance provided as standard the base unit is already very capable but when combined with optional measurement modes and sampling accessories in addition to the new Simultaneous Multi-Probe (SMP) acquisition system you can unleash the power only dreamed of by earlier systems
The Dual Polarizing Prism Monochromator is enhanced for performance into the Vacuum UV region with excellent stray-light rejection for accurate results.
While the UV and Visible performance has been optimized the J-1500 can meet demands well into the NIR region. An optional PMT will extend the range to1250nm and a special detector and light source can be added to extend the range to 1600nm.
| Measurement Modes
The wide range of measurement modes available delivers a true chiroptical spectroscopy workbench. One spectrometer can measure CD, LD, Absorbance as standard. Optional modes include Fluorescence, Fluorescence Detected CD, Fluorescence Detected LD, Fluorescence Polarization/Anisotropy, Optical Rotatory Dispersion, Magnetic CD, Stopped flow CD/Abs/Fluorescence and more.
| Simultaneous Multi-Probe (SMP)
The SMP technology delivers a new level of productivity that looks at your sample using several techniques at the same time to extract maximal information in minimal time.
CD is easily monitored while altering conditions such as temperature, pH, solvent and buffer or binding and rapid kinetics to determine optimize long term stability or otherwise determine the dynamic properties of biomolecules.
This auto-sampling CD system utilized 96 well micro-titor plates for completely unattended measurement of up to 192 samples. Samples are kept at a constant temperature while waiting for measurement which can include both spectral and temperature scanning. An adjustable wash cycle is performed between each sample which can be preserved and returned to the micro-plate for further analysis.
You work hard for your samples and sometimes they are very limited. Amazing new accessories for the J-1000 allow you to measure excellent CD data from as little as a 5ul sample.
Integrated Hg lamp for wavelength calibration and scale calibration material purity validated using NIST certified standards.
Computerized gas flow modeling was utilized to design the flow of the purge gas to optimize the flow efficiency to purge the fastest and most efficiently throughout the optical system without user intervention.
Only a standard USB2 connection is made between the PC and the CD system assuring that future PC changes are easy to make without concern of compatibility specialized boards placed in the PC.
Only JASCO CD systems are manufactured to the internationally recognized standards of the ISO quality program assuring you a product which consistently meets guaranteed specifications and a quality level that is defined and unsurpassed.
Advanced Application of CD Measurement for Pharmaceutical Research
Analyzing the interaction of human serum albumin and 3,5-diiodosalicylic acid
Spectra Manager II Spectroscopy Software Suite
The new Jasco J-1000 Series utilizes the Spectra Manager II Spectroscopy Software Suite that is common with all other Jasco spectroscopy instrumentation. Spectra Manager II is a 64 bit program designed for Windows 7 and is a complete suite offering data acquisition, analysis and presentation in Canvas a publication quality printing and display module.
Optimized for multi-user environments Spectra Manager II can be very simple to operate but still offer the flexibility required for complex experiments. Measurement parameters are easy to store and retrieve for frequent measurements and a Macro command module allows automation of complex measurements including analysis and even printing to pre-set templates in the Canvas module.
User customizable toolbars are provided for frequently used functions. Analysis functions designed for CD data include integrated algorithms for Secondary Structure Analysis and conversion of various Optical Constant units. Thermal analysis functions include determination of Tm, enthalpy and entropy and a protein-ligand binding calculation program is available for use with the titration system.
Spectra Manager CFR is available for laboratories falling under the FDA mandate 21CFR11. The interface to the PC is simple a USB port allowing the PC to change easily in the future as new operating systems evolve.
Sample screen shots below:
|PTC-517||Single Cell Peltier Holder|
|MPTC-511||Automatic 6-Position In-Line Peltier Cell Changer|
|MPTC-513||Automatic 6-Position Turret Peltier Cell Changer|
|HTCD-1500||High-throughput CD System|
|EXPM-531||Extended Wavelength Detector to 1200nm (ExPMT)|
|EXIG-532||Extended Wavelength Detector to 1600nm (InGaAS)|
|ATS-530||Automatic Titration System|
|PML-534||FDCD Detector (PMT)|
|FDCD-551||Artifact Free FDCD Unit|
|EXPML-535||Extended FDCD detector to 1200nm|
|EXIGL-536||Extended FDCD detector to 1600nm|
|CFC-574||LD/CD Couette flow cell|
|SFS-562||Two Syringe Stopped-Flow System|
|SFS-562T||Two Syringe Stopped-Flow System with Temperature Control|
|SFS-563||Three Syringe Stopped-Flow System|
|SFS-563T||Three Syringe Stopped-Flow System with Temperature Control|
|SFS-564||Four Syringe Stopped-Flow System|
|SFS-564T||Four Syringe Stopped-Flow System with Temperature Control|
|HTC-572||Pressure-induced Ultra High-Temperature Measurement Cell|
|DRCD-574||Solid Sample Measurement Unit (BaSO 4 coating)|
|DRCD-575||Solid Sample Measurement Unit (Spectralon coating)|
|PM-491||1.6T Tesla Permanent Magnet MCD Unit|
|MCD-581||1.5 Tesla Variable Field Electromagnet|
|CRYS-582||Cryostat for solid samples|
|CRYL-583||Cryostat for liquid samples|
|SSCD-576||IR Style Sample Holder|
|ORDM-520||High Accuracy Optical Null ORD Unit|
|ORDE-521||Electrical Null ORD Unit|
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