The use of supercritical fluids offers a green alternative to traditional HPLC with the use of CO2 in place of organic solvents. This reduction offers cost, health, and safety benefits, as well as faster, cleaner sample recovery during material purification. Other advantages of supercritical fluids include the liquid-like densities, for higher solubility and increased column loading. The low viscosity and highly diffusion lead to faster separations and faster extractions.

SFC has long been the method of choice for chiral separations, but with the large range (and growing rapidly) of column phases available – SFC is now becoming a powerful tool for achiral separations, both analytically and for sample prep.

JASCO SFC System Advantage

Optimized

JASCO has been developing packed column SFC and SFE systems for more than 30 years; the continual development process has resulted in the new 4000 series being even more user friendly, robust and productive.

Patented High-Speed Regulator

The 4000 series high-speed dynamic back-pressure regulator ensures that a constant back pressure is maintained at all times, regardless of the flow rate and with virtually no hysteresis. The extremely low dead volume prevents fractions from remixing and prevents precipitation build-up in the flow line.

Wide Range of Detectors

Single wavelength UV-visible, PDA and the CD-4095 the only chiral detector suitable for SFC. Non-optical detectors include FID, ELSD and single-quad mass-spec.

Flexible

All 4000 series SFC systems can be used for HPLC, simply switch off the cooling and BPR.

Integrated Modular System

The basic system for each scale can be adapted to suit your application. From modifier selection to column heater type to detector combinations.

Compatible

JASCO SFC systems are compatible with most Mass Spectrometers and offer direct control in both Thermo Xcalibur and Sciex Analyst software.

Unparalleled Customer Service

JASCO provides professional, fast and courteous support on all of our products. We have service centers strategically located throughout the U.S. to ensure the highest level of customer satisfaction. Our scheduled and on-site training classes are available for advanced application training.

Multiple Configurations

JASCO offers multiple configurations, please contact us to discuss your requirements in detail.